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Wyndham Houston - Medical Center Hotel and Suites

  • 6800 Main Street
  • Houston, TX 77030 US
  • 1-713-528-7744
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4.05Average TripAdvisor Overall Rating of 4.0 of 5 for Wyndham Houston - Medical Center Hotel and Suites
Wyndham Houston - Medical Center Hotel and Suites
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Review, change, or cancel reservations made on If you need additional assistance, please call 877-999-3223 (1-506-638-4899 outside the U.S. and Canada).

During the Rodeo event (February 24th through March 27th, 2016), we cannot allow parking for buses, trailers or large vehicles in the parking lot. Single parking spaces only.

Best of the Full-Service Hotels Near Houston's NRG Reliant Stadium and Medical Centers

At the Wyndham Houston Hotel & Suites Medical Center – a modern oasis in the heart of Texas Medical Center – 75% of the 287 guest rooms are spacious, comfortable suites featuring kitchens with microwave, fridge, stovetop, dishwasher, toaster and dining tables. Some rooms feature a sleeper sofa for added comfort.  Since this Houston hotel is just two blocks from the METRO rail, guests can easily access Houston's array of medical centers (MD Anderson Center Cancer Center, Saint Luke's Health System, Texas Medical Center, UT Health Science Center, and the Texas Children's Hospital), Houston's superb institutions (Rice University, The University of Houston, and Texas Southern University), Houston's esteemed entertainment attractions (including The Museum District, The Houston Zoo and Kipp Aquarium, Discovery Green, the Houston Livestock Show and Rodeo, and the downtown Houston theatre district), and its year-round sports offerings (at Minute Maid Park, Toyota Stadium, and NRG Reliant Stadium).

Guests on vacation, as well as guests looking for extended stay accommodations, enjoy onsite swimming, exercising and dining, year-round at this Houston full-service hotel. 

Delicious room service and free shuttle, accessing many local destinations, make this smoke-free hotel in Houston, TX an ideal getaway spot. Free Wi-Fi, onsite parking and same day dry cleaning are convenient for business travelers. 

With practically something for everyone, this Houston, TX hotel is the discerning traveler’s best friend.

Visit Wyndham Houston Hotel & Suites - Ideal for Medical, Business or Leisure Travel

Some of the greatest medical institutions in the world call Houston their home: Texas Medical Center, MD Anderson Cancer Center, UT Health Science Center and more. But this bustling metropolis is also a great spot for University travelers: Texas Southern University, Rice University and the University of Houston are all primarily located in Houston. Space enthusiasts will want to visit Space Center Houston and NASA’s mission control room at Johnson Space Center. The Houston theater district is a popular, 17-block downtown destination. Sports fans will be entertained year round, whether at nearby Minute Maid Park for an Astros game, at Toyota Stadium to see the Rockets run the court, or at NRG Reliant Stadium for a Texans football brawl -- all located within walking distance from the hotel, in case you don't want to enjoy a swift ride on the light rail.

With temperatures in the 60’s through the 90’s year-round, Houston is a fantastic spot for cycling, urban exploration, parks and recreation activities, parade and festival attendance, and playing golf. Visit Houston now for business and pleasure.